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Pradheep Chhalliyil



Dr. Pradheep Challiyil is a scientist, educator and an author of several books.

He is now a Biotechnology consultant working to solve challenges in the application of RNA, DNA for molecular biology applications like qPCR, Digital PCR, DAN sequencing etc. 

Dr. Chhalliyill has 30 plus years of professional scientific experience. In 1997, Dr. Challiyil co-founded a 503(c) tax-exempt non-profit organization called Sakthi Foundation. He also started a Sakthi Schools, a subsidiary of Sakthi Foundation. Today, there are several Sakthi Schools operation in Southern India. In addition, he developed a new effective, integrated and holistic education system known as the Uni5 system of education. In fact, all the Sakthi Schools, as well as few other schools in India, are adopting this Uni5 system of education.

Sakthi Foundation website will provide an immense amount of information ranging from health, happiness, relationship, pattern-based education, parenting, energy, and spirituality. He has delivered numerous lectures all around the globe. He also provides advice through Uni5 telegram groups on the above topics.



A Biotechnology consultant for solving challenges in the application of RNA, DNA for molecularbiology applications like qPCR, Digital PCR, DAN sequencing etc. 

 Senior Scientist: Worked on developing molecular biology  technology (qPCR, digital PCR etc) to help food industry to test for food fraud, adulteration, contamination etc.

prad 2016 maySocial responsibility:   Co-founded and works at free time for a community-profiting organization (Uni5-SakthiFoundation INC).

Co-started a five level integrated Holistic Education Uni5 Schools in India.

Gives awareness talks on aspects of life (Health, Relationships, Parenting, Education, Spirituality, Selftuality and Community Responsibility).

Education Background

  • Ph.D in Cancer Biology, Madurai Kamaraj University, Madurai, India
  • Post doctoral Fellow, Roswell Park Cancer Institute, Buffalo, NY.
  • M. S. Biochemistry PSGCAS, Coimbatore (India)
  • B. S. Biochemistry PSGCAS, Coimbatore (India)

Importance of Ph.D work in Cancer : This work was the first to show the effect of Clesitanthin compounds purified from cleistanthus collinus on cancer cells with least effect on normal cells in comparison to other leading cancer drugs. Cleistanthus collinus is a toxic plant , but purification results in removing the toxic effects and showing anticancerous activity.

This work is still motivating other researchers to work on these compounds.  Godvari Refinieries ,  Sathgen,  a company has studied the effect on clesitanthin and its derivatives. 

A pub med search



  • The first “Anna Memorial GOLD AWARD”, for the best Ph.D. thesis publication in cancer field (India).
  • Winner-Book Award 2004 at Hollywood Spiritual Film Festival



  • A process for isolation of the anticancer principle from medicinal plants - India - 1539/MAS/95.
  • An electrochemical process for water sterilization by singlet Oxygen production - 1622/MAS/95.


  • Deivamum Deiveega Sakthigalum:
  • Journey to the Source, Decoding Matrix Trilogy, Sakthi Books 2004, Iowa.
  • “Putrunoyyium Unavum” (Diet & Cancer- Co-author Dr.M.Madeswaran) Tamil, 1997, Maruthi Publishers, Coimbatore, India.
  • "Bhakshanavum Cancerum" Malaylam, Sakthi Foundation 2013, USA - Co-Author-Dr.M.Thomas).
  • More than 2000 pages of information on web on Health, Relationships, Parenting, Education, Spirituality, Selftuality and Community Responsibility.

Ph.D Work: Cleistanthin as Anti-cancer agent

News in "The Hindu"

News in Tamil Paper

News in Malayalam Paper 

Scientific Publications:

Work quoted in Book


ALTERNATIVES TO THE USE OF LIVE VERTEBRATES IN BIOMEDICAL RESEARCH AND TESTING : A bibliography with Abstracts: Prepared by NATIONAL LIBRARY OF MEDICINE NATIONAL INSTITUTES OF HEALTH BETHESDA, MD Vera W. Hudson, M.S. Project Coordinator and Scientific Editor, National Library of Medicine and Elizabeth DeBerry, Copy Editor, National Library of Medicine: 1997 No. 3.

Cytotoxic and genotoxic effects of cleistanthin B in normal and tumor cells. Prabhakaran C Kumar P, Panneerselvam N, Rajesh S, Shanmugam G.

2. Quick Tips for Balanced Living:Himalayan Institute Press-2005. Inner Cleansing by Pradheep Chhalliyil -Page 32-34.

3. From Superman to Brahman: The Religious Shift of The Matrix Mythology    

Journal of Religion and Film, Jeffery Wittung, Daniel Bramer Volume 10 Issue 2 October 2006



 Co-Founded Uni5 Sakthi Foundation INC

  • A Tax exempted Non-Profit (Community Profiting) organization operating in USA, India, and Indonesia and doing various charitable activities.
  • Giving health information to hundreds of people all over the globe for various ailments.
  • Help to fund underprivileged children, orphans for their school education.
  • Bring awareness among underprivileged people through health camps, such as “eye camps”, and diabetic camps in remote areas of Tamil Nadu.
  • Create Audiovisual materials to help create health awareness.
  • Started the first free or pay-as-capable Uni5schools in Sendurai (Madurai), Coimbatore, Porayar (as opposed to middle/upper-class oriented schools in urban locations). (
  • Support the work of other non-profit (NGO's) organizations.

 TEACHING EXPERIENCE (1990 to 1997):

  • Lecturer in Biochemistry, P.S.G.College of Arts & Sciences, CBE, Dec 1990 – May 1992.
  • Biochemistry theory & practicals for MSc Biology and Biotechnology at M. K. University (1992 -97).


    • UGC Lectureship 1990 (University Grants Commission)
    • ICAR Biotechnology 1991 (Indian council of Agri.Research)
    • UGC-CSIR JRF 1992 (Council of Scientific & Industrial Research).
    • UGC-CSIR SRF 1994 (Council of Scientific & Industrial Research).

    1. C.P.Pradheepkumar, & G.Shanmugam. "Cleistanthin B induces cell death by causing DNA damage". Proc.Nat.con. on environ, health & genetic risk at Osmania University at Hyderabad on 5-6 Nov. 1995.

    2. C.P.Pradheepkumar, Sapna Sinha, N.Panneer selvam & G.Shanmugam. "Apoptosis & genotoxic effects of anticancer drugs & herbicides"National symposium on Apoptosis mech.s & applns. March 7-8,1996.

    3. G.Shanmugam, C.P.Pradheepkumar & N.Panneerselvam. "Apoptosis induced by Cleistanthin B in CHO cells" 6th Int.congress on Cell Biology & 36th Amer. Soc. for cell biol annual meeting Dec 7-11,1996, San Francisco, California.

    4. First International Comprehensive Cancer Care conferance: Center for mind-body medicine. 12-14th June 1998, Washington DC, USA (Full scholarship was given to attend the conference).

    5. First International congress on Tibetian Medicine: 7-9th Novemeber 1998, Washington DC, USA (Full scholarship was given to attend the conference).

    6. 1st Global Conference on GMO Analysis, Villa Erba, Como, Italy, 24-27 June 2008, GM rice screening in the Mexican market by real time PCR

    7. Pittcon Conference 2007, 2009, 2012

    8. PAG Plant Animal Genome conference – 2008, 2012

    9. Real-Time Conference - 2007

  • G-OnRamp Workshop Agenda 2018 Washington University in St. Louis, July 16-19

Links to Talks

Topics of Talks

1. Health and luck factor !. More modern scientific research shows that more than genetics, environment and life style, diseases like cancer is caused by randomness. The talk will be about luck in life, how to understand it and how to increase it. The content is totally different from the common views of information not thought about by doctors or health professionals.

2. Successful Parenting !. This topic is about the five needs of a child that is taken care from the young age will guarantee success in a child's life. This will help to avoid stress both in the parents and the child. This is based on practically tried and found effective.

3. Happy and successful Carreer !.This talk helps adults and students to find the job enjoyable and successful. It also addresses what career one should choose and find happiness in all five levels of being.

4. Simplified Bhagavad Gita !.One of the most practical solutions for all day to day life problems we encounter. This one hour talk will give you the essence of Gita that you it will make sense the geniousness of the Ancient Indian thought on encountering life situations.

5. Can one Education pattern be effective for effective personal and professional life !. This talk brings evidence how a pattern based education can help all students, adults about a pattern based learning system that will make one brilliant in arts, science, maths and at the same time understand the mystery of oneself and the Universe.

Chhalliyil, P.; Ilves, H.; Kazakov, S.A.; Howard, S.J.; Johnston, B.H.; Fagan, J. A Real-Time Quantitative PCR Method Specific for Detection and Quantification of the First Commercialized Genome-Edited Plant. Foods20209, 1245.

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